Prospects for eradication of meningococcal disease
نویسنده
چکیده
Meningococcal meningitis and septicaemia remain a serious global health threat. This review focuses on the epidemiology of meningococcal disease following the recent implementation of effective vaccines and the potential utility of a vaccine against serogroup B meningococcus.
منابع مشابه
Immunological Aspect of Meningococcal disease: An overview in Host- Bacteria Interaction
Meningococcal disease remains a significant global public health and is unique among causes of bacterial meningitis and sepsis where it not only causes sporadic disease but also outbreaks. Meningococcal disease has a rapid onset with high mortality. The understanding of immunopathogenesis is crucial for development of novel therapeutic strategies and vaccines designed against meningococcal dise...
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Invasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully implemented a single dose of meningococcal serogroup C conjugate vaccine at the age of 14 months a...
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Comment Strains of meningococci carried in the general population usually belong to non-virulent serological groups and types, even during an epidemic, and hence the ratio of attacks to carriers is low3; in Denmark in 1987 it was 1:17000 (297 cases in a population of 5-1 million). If the secondary attack rate among household contacts of an index case of meningococcal disease is 500-800 times th...
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